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CyFlow™ CD28 Low Endotoxin

CyFlow™ CD28 Low Endotoxin
Alternative Name: Tp44
Antibody: Yes
Antigen: CD28
Application: Flow cytometry, Functional assays, Immunocytochemistry, Immunohistochemistry (frozen sections), Immunoprecipitation
Clonality: monoclonal
Clone: 37.51
Field of Interest: Immunophenotyping, MHC
Format/Fluorochrome: Low Endotoxin
Isotype: IgG
Regulatory Status: RUO
Source Species: Hamster
Target Species: Mouse
Product number: CN951297

For Research Use Only

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Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
CyFlow™ CD28 Low Endotoxin
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenMouse T cell lymphoma EL-4 cells
Background InformationCD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ T cells express CD28. In the thymus, CD28 expression is highest on immature CD3-, CD8+ and CD4+8+ cells, and on CD4-8- cells that express α/β and γ/δ TCR. The level of CD28 on mature CD4+ and CD8+ α/β TCR+ thymocytes is two- to fourfold lower than on the immature cells.
Storage BufferThe reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Specific References

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