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CyFlow™ HLA-Class I Purified

CyFlow™ HLA-Class I Purified
Antibody: Yes
Antigen: HLA-Class I
Application: Enzyme-linked immunosorbent assay, Flow cytometry, Immunoprecipitation
Clonality: monoclonal
Clone: MEM-123
Field of Interest: MHC
Format/Fluorochrome: Purified
Isotype: IgG3
Regulatory Status: RUO
Source Species: Mouse
Target Species: Cow, Human, Non-Human Primates
Product number: AN366080

For Research Use Only

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Description
Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
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CyFlow™ HLA-Class I Purified
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenCOS-7 African green monkey kidney cells
Background InformationHLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant β2-microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumor defense. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Specific References

| Van Den Berg CW, De Andrade RM, Magnoli FC, Marchbank KJ, Tambourgi DV: Loxosceles spider venom induces metalloproteinase mediated cleavage of MCP/CD and MHCI and induces protection against C‐mediated lysis. Immunology. 2002 Sep; 107(1):102-10. < PMID: 12225368 > | van den Berg CW, Gonçalves-de-Andrade RM, Magnoli FC, Tambourgi DV: Loxosceles spider venom induces the release of thrombomodulin and endothelial protein C receptor: implications for the pathogenesis of intravascular coagulation as observed in loxoscelism.. J Thromb Haemost. 2007 May; 5(5):989-95. < PMID: 17229042 > | Bonomi A, Coccè V, Cavicchini L, Sisto F, Dossena M, Balzarini P, Portolani N, Ciusani E, Parati E, Alessandri G, Pessina A: Adipose tissue-derived stromal cells primed in vitro with paclitaxel acquire anti-tumor activity. Int J Immunopathol Pharmacol. 2013 Jan-Mar; 26(1 Suppl):33-41. < PMID: 24046947 > | Punyadee N, Mairiang D, Thiemmeca S, Komoltri C, Pan‐Ngum W, Chomanee N, Charngkaew K, Tangthawornchaikul N, Limpitikul W, Vasanawathana S, Malasit P, Avirutnan P: Microparticles provide a novel biomarker to predict severe clinical outcomes of dengue virus infection.. J Virol. 2015 Feb; 89(3):1587-607. < PMID: 25410854 >

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