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CyFlow™ CD24 Purified

CyFlow™ CD24 Purified
Alternative Name: BA 1 , HAS
Antibody: Yes
Antigen: CD24
Application: Flow cytometry, Immunohistochemistry (frozen sections)
Clonality: monoclonal
Clone: SN3
Field of Interest: Immunophenotyping
Format/Fluorochrome: Purified
Isotype: IgG1
Regulatory Status: RUO
Source Species: Mouse
Target Species: Human
Product number: BH532849

For Research Use Only

HLDA Workshop HLDA IV—WS Code B 136 HLDA V—WS Code B CD24.7 Concentration Unit mg/mL... more
CyFlow™ CD24 Purified
HLDA WorkshopHLDA IV—WS Code B 136 HLDA V—WS Code B CD24.7
Concentration Unitmg/mL
Quantity0.1 mg
Volume0.1 mL
ImmunogenGlycoproteins purified from human NALM-1 cell line
Background InformationCD24 (BA 1, HSA) is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4; it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Specific References

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