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CyFlow™ CD45R0 Purified

CyFlow™ CD45R0 Purified
Alternative Name: UCHL-1
Antibody: Yes
Antigen: CD45R0
Application: Flow cytometry, Immunohistochemistry, Immunoprecipitation
Clonality: monoclonal
Clone: UCHL1
Field of Interest: Immunophenotyping, Phosphorylation
Format/Fluorochrome: Purified
Isotype: IgG2a
Regulatory Status: RUO
Source Species: Mouse
Target Species: Human
Product number: AA887536

For Research Use Only

HLDA Workshop HLDA III—WS Code NL 826 HLDA III—WS Code T 128 HLDA IV—WS Code NL 31 HLDA V—WS... more
CyFlow™ CD45R0 Purified
HLDA WorkshopHLDA III—WS Code NL 826 HLDA III—WS Code T 128 HLDA IV—WS Code NL 31 HLDA V—WS Code BP BP460 HLDA V—WS Code T T-081 HLDA V—WS Code T T-CD45.43
Concentration Unitmg/mL
Quantity0.1 mg
Volume0.1 mL
ImmunogenHuman IL-2 dependent T cells
Background InformationCD45R0 (UCHL-1) is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45R0 is expressed e.g. on macrophages, CD8+ T cells, activated T cells and myeloma cells.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Specific References

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