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CyFlow™ CD46 Azide Free

CyFlow™ CD46 Azide Free
Alternative Name: MCP
Antibody: Yes
Antigen: CD46
Application: Flow cytometry, Immunoprecipitation, Western blot
Clonality: monoclonal
Clone: MEM-258
Field of Interest: Immunophenotyping
Format/Fluorochrome: Azide Free
Isotype: IgG1
Regulatory Status: RUO
Source Species: Mouse
Target Species: Cow, Human
Product number: BZ758453

For Research Use Only

Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
CyFlow™ CD46 Azide Free
Concentration Unitmg/mL
Quantity0.1 mg
Volume0.1 mL
ImmunogenHuman Acute Lymphocytic Leukemia (ALL) T cells
Background InformationCD46 (MCP; membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.
Storage BufferThe reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Specific References

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