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CyFlow™ CD80 PE-Cy7

CyFlow™ CD80 PE-Cy7
Alternative Name: B7- B7-1 , BB1
Antibody: Yes
Antigen: CD80
Application: Flow cytometry
Clonality: monoclonal
Clone: MEM-233
Emission Maximum: 785 nm
Excitation Maximum: 496 nm, 565 nm
Field of Interest: Immunophenotyping
Format/Fluorochrome: PE-Cy7
Isotype: IgG1
Laser: Blue , Green, Yellow
Regulatory Status: RUO
Source Species: Mouse
Target Species: Human
Product number: AR682958

For Research Use Only

Quantity 100 tests Volume 0.4 mL Immunogen Extracellular domain of human CD80 fused... more
CyFlow™ CD80 PE-Cy7
Quantity100 tests
Volume0.4 mL
ImmunogenExtracellular domain of human CD80 fused to human IgG1(Fc)
Background InformationCD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CD152 (CTLA-4). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 4·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Specific References

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