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CyFlow™ CD101 PE

CyFlow™ CD101 PE
Alternative Name: P126, V7
Antibody: Yes
Antigen: CD101
Application: Flow cytometry
Clonality: monoclonal
Clone: BB27
Emission Maximum: 576 nm
Excitation Maximum: 496 nm, 565 nm
Field of Interest: Immunophenotyping
Format/Fluorochrome: PE
Isotype: IgG1
Laser: Blue , Green, Yellow
Regulatory Status: RUO
Source Species: Mouse
Target Species: Human
Product number: AA570768

For Research Use Only

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Description
Quantity 100 tests Volume 1.0 mL Immunogen Human thymic clone B12 Background... more
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CyFlow™ CD101 PE
Quantity100 tests
Volume1.0 mL
ImmunogenHuman thymic clone B12
Background InformationCD101 is a type I transmembrane glycoprotein, which forms disulfide-linked homodimers. It is expressed on activated T cells, as well as on granulocytes, monocytes, dendritic cells or mucosal T cells. It plays a major role in the activation of T cells by skin dendritic cells. Function of CD101 has not been fully elucidated, but in mice its knock-out results in liver autoimmune disease induced by Novosphingobium aromaticivorans.
UsageThe reagent is designed for Flow Cytometry analysis of human blood cells. Recommended usage is 10·µl reagent·/ 100·µl of whole blood or 10^6 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Storage BufferThe reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Specific References

| Doussis IA, Gatter KC, Mason DY: CD68 reactivity of non‑macrophage derived tumours in cytological specimens. J Clin Pathol. 1993 Apr; 46(4):334‑6. < PMID: 7684403 > | Bagot M, Martinel I, Charue D, Boulland ML, Wechsler J, Bensussan A, Boumsell L: Functional role of CD101 on skin dendritic cells. Adv Exp Med Biol. 1997; 417:227‑32. < PMID: 9286366 > | Bagot M, Martinel I, Charue D, Weill F, Boulland ML, Wechsler J, Freeman GJ, Bensussan A, Boumsell L: CD101 is expressed by skin dendritic cells: Role in T‑lymphocyte activation. Tissue Antigens. 1997 Nov; 50(5):439‑48. < PMID: 9389317 > | Grassi F, Dezutter-Dambuyant C, McIlroy D, Jacquet C, Yoneda K, Imamura S, Boumsell L, Schmitt D, Autran B, Debré P, Hosmalin A: Monocyte‑derived dendritic cells have a phenotype comparable to that of dermal dendritic cells and display ultrastructural granules distinct from Birbeck granules. J Leukoc Biol. 1998 Oct; 64(4):484‑93. < PMID: 9766629 >

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