CyFlow™ CD103 Purified
![CyFlow™ CD103 Purified](https://la-en.sysmex-flowcytometry.com/media/image/0e/19/4b/Cyflow-bottle-2-with-RUO-label_600x600.png)
Alternative Name: | HML-1 , Integrin αE-subunit |
Antibody: | Yes |
Antigen: | CD103 |
Application: | Flow cytometry, Immunohistochemistry (frozen sections), Immunoprecipitation, Western blot |
Clonality: | monoclonal |
Clone: | Ber-ACT8 |
Field of Interest: | Immunophenotyping |
Format/Fluorochrome: | Purified |
Isotype: | IgG1 |
Regulatory Status: | RUO |
Source Species: | Mouse |
Target Species: | Human, Non-Human Primates |
Product number: | BK166852 |
For Research Use Only
HLDA Workshop | HLDA V—WS Code A067 |
Concentration Unit | mg/mL |
Concentration | 1 |
Quantity | 0.1 mg |
Volume | 0.1 mL |
Immunogen | HTLV 1-induced human T cell line MAPS16 |
Background Information | CD103 (Integrin αE) is an integrin subunit that is expressed on intraepithelial lymphocytes, epithelial dendritic cells, lamina propria-derived dendritic cells, a subpopulation of lamina propria T cells, a small subset of peripheral lymphocytes, namely T reg cells, and on activated and TGF-β stimulated lymphocytes. CD103 is in mature form cleaved into two disulfide-linked chains (C-terminal 150 kDa chain and N-terminal 25 kDa chain). It heterodimerizes with integrin β7 subunit to form αE/β7 integrin (mucosal lymphocyte 1 antigen), which through binding E-cadherin mediates homing of lymphocytes to the intestinal epithelium, and, in addition to the role in adhesion, may serve as an accessory molecule for intraepithelial lymphocyte activation. |
Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide. |
Storage | Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze. |
Stability | Do not use after expiration date stamped on vial label. |
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