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CyFlow™ CD103 Purified

CyFlow™ CD103 Purified
Alternative Name: HML-1 , Integrin αE-subunit
Antibody: Yes
Antigen: CD103
Application: Flow cytometry, Immunohistochemistry (frozen sections), Immunoprecipitation, Western blot
Clonality: monoclonal
Clone: Ber-ACT8
Field of Interest: Immunophenotyping
Format/Fluorochrome: Purified
Isotype: IgG1
Regulatory Status: RUO
Source Species: Mouse
Target Species: Human, Non-Human Primates
Product number: BK166852

For Research Use Only

HLDA Workshop HLDA V—WS Code A067 Concentration Unit mg/mL Concentration 1... more
CyFlow™ CD103 Purified
HLDA WorkshopHLDA V—WS Code A067
Concentration Unitmg/mL
Quantity0.1 mg
Volume0.1 mL
ImmunogenHTLV 1-induced human T cell line MAPS16
Background InformationCD103 (Integrin αE) is an integrin subunit that is expressed on intraepithelial lymphocytes, epithelial dendritic cells, lamina propria-derived dendritic cells, a subpopulation of lamina propria T cells, a small subset of peripheral lymphocytes, namely T reg cells, and on activated and TGF-β stimulated lymphocytes. CD103 is in mature form cleaved into two disulfide-linked chains (C-terminal 150 kDa chain and N-terminal 25 kDa chain). It heterodimerizes with integrin β7 subunit to form αE/β7 integrin (mucosal lymphocyte 1 antigen), which through binding E-cadherin mediates homing of lymphocytes to the intestinal epithelium, and, in addition to the role in adhesion, may serve as an accessory molecule for intraepithelial lymphocyte activation.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Specific References

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