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CyFlow™ CD107a Azide Free

CyFlow™ CD107a Azide Free
Alternative Name: LAMP-1
Antibody: Yes
Antigen: CD107a
Application: Flow cytometry, Immunocytochemistry, Immunohistochemistry, Western blot
Clonality: monoclonal
Clone: H4A3
Field of Interest: Immunophenotyping
Format/Fluorochrome: Azide Free
Isotype: IgG1
Regulatory Status: RUO
Source Species: Mouse
Target Species: Human, Mouse, Non-Human Primates
Product number: AC942051

For Research Use Only

Concentration Unit mg/mL Concentration 1 Quantity 0.1 mg Volume 0.1 mL... more
CyFlow™ CD107a Azide Free
Concentration Unitmg/mL
Quantity0.1 mg
Volume0.1 mL
ImmunogenHuman peripheral blood mononuclear cells (PBMC)
Background InformationCD107a (LAMP-1; lysosome-associated membrane protein-1), together with CD107b (LAMP-2), is a major constituent of lysosomal membrane, 1-2 % of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.
Storage BufferThe reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Specific References

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