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CyFlow™ CD117 Purified

CyFlow™ CD117 Purified
Alternative Name: c-kit , SCFR
Antibody: Yes
Antigen: CD117
Application: Flow cytometry, Immunocytochemistry, Immunohistochemistry (frozen sections), Immunoprecipitation
Clonality: monoclonal
Clone: 104D2
Field of Interest: Immunophenotyping, Phosphorylation
Format/Fluorochrome: Purified
Isotype: IgG1
Regulatory Status: RUO
Source Species: Mouse
Target Species: Cow, Human, Non-Human Primates
Product number: AH410546

For Research Use Only

HLDA Workshop HLDA VI—WS Code C-30 Concentration Unit mg/mL Concentration 1... more
CyFlow™ CD117 Purified
HLDA WorkshopHLDA VI—WS Code C-30
Concentration Unitmg/mL
Concentration1
Quantity0.1 mg
Volume0.1 mL
ImmunogenMOLM-1 megakaryocytic cells
Background InformationCD117 (c-Kit) is a 145 kDa receptor tyrosine kinase that regulates cell proliferation, adhesion, chemotaxis, apoptosis and other cell processes. Mutations of CD117 can lead to growth and progression of tumors. After binding of its ligand, SCF (stem cell factor), CD117 is autophosphorylated on its intracellular domains and activated. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells and various cancer cells, e.g. acute myeloid leukemia cells.
Storage BufferThe reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
StorageAvoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
StabilityDo not use after expiration date stamped on vial label.
Specific References

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